Chameleon™ COLOREX™ COL-APSE (RUO)
Chameleon™ COLOREX™ COL-APSE prepared culture media plates by S²Media are manufactured using original CHROMagar™ raw materials. This selective chromogenic culture medium is intended for the isolation and differentiation of colistin-resistant Gram-negative bacteria from human, veterinary, and environmental specimens. The medium supports recovery of organisms with intrinsic or acquired polymyxin resistance, including plasmid-mediated MCR mechanisms, while chromogenic colony characteristics facilitate presumptive differentiation of resistant pathogens. With a reported limit of detection of 10 CFU/mL, COL-APSE provides a sensitive screening tool for surveillance of colistin resistance and emerging antimicrobial resistance mechanisms in complex sample matrices.
👉 Key Performance Features:
Chromogenic Differentiation: Characteristic colony coloration facilitates presumptive differentiation of colistin-resistant E. coli, other coliforms, Pseudomonas, and Acinetobacter spp.
High Sensitivity: Demonstrated 100% sensitivity for the recovery of colistin-resistant Gram-negative organisms.
Selective Performance: Demonstrated 81% specificity, with a 100% negative predictive value (NPV) and 83% positive predictive value (PPV) in published performance evaluation.
Low Limit of Detection: Demonstrated detection limit of 10 CFU/mL, supporting recovery of low-level colistin-resistant populations.
Rapid Detection: Results can be interpreted after 18-24 hours of aerobic incubation at 35-37°C.
Direct Colonization Screening: Supports direct screening of rectal swabs, perineal swabs, and stool specimens for gastrointestinal colonization with colistin-resistant Gram-negative bacteria.
Broad Surveillance Utility: Applicable to human, veterinary, food, animal feed, livestock, and environmental samples for surveillance of colistin resistance, including organisms with acquired resistance mechanisms such as MCR.
📌 This product is labeled for Research Use Only (RUO).
👉 Finished product meets the following standards and references:
CLSI
🧫 Application Areas:
Clinical microbiology for the selective detection and differentiation of colistin-resistant Gram-negative bacteria
Gastrointestinal colonization screening for colistin-resistant and multidrug-resistant organisms (MDROs)
Infection prevention and healthcare-associated infection (HAI) surveillance
Antimicrobial resistance (AMR) and emerging resistance surveillance
Veterinary and livestock microbiology
Food and animal feed safety testing
Environmental monitoring and antimicrobial resistance surveillance
Public health and epidemiological surveillance
Equivalent or Comparable to Item Numbers:
CHRP0023
70-C00121
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