Chameleon™ COLOREX™ VRE (RUO)
Chameleon™ COLOREX™ VRE prepared culture media plates by S²Media are manufactured using original CHROMagar™ raw materials. This selective chromogenic culture medium is intended for the qualitative direct detection and differentiation of vanA/vanB-type vancomycin-resistant Enterococcus faecium and Enterococcus faecalis (VRE) from rectal swabs and stool specimens. Following 24 hours of aerobic incubation at 35-37°C, characteristic colony coloration facilitates rapid presumptive identification of transmissible VRE, supporting gastrointestinal colonization screening, infection prevention, and antimicrobial resistance surveillance in healthcare settings. VRE is not intended to diagnose infection or guide antimicrobial therapy. Presumptive isolates should be confirmed by appropriate organism identification, antimicrobial susceptibility testing, and epidemiological characterization.
👉 Key Performance Features:
Rapid, Direct VRE Detection: Enables direct screening for vanA/vanB-type vancomycin-resistant E. faecium and E. faecalis, supporting timely implementation of infection control measures.
High Analytical Performance: Demonstrated 100% sensitivity and 100% specificity following 24 hours of aerobic incubation at 37 °C.
High Clinical Sensitivity: Demonstrated 95.5% sensitivity and 90.4% specificity with rectal swab specimens after 24 hours at 35-37°C, compared with 68.2% sensitivity and 91.8% specificity for the reference VRE Select medium.
Distinct Chromogenic Differentiation: Intense, characteristic colony colors facilitate presumptive differentiation of vancomycin-resistant E. faecium and E. faecalis.
Improved Plate Interpretation: Chromogenic differentiation avoids the diffuse blackening associated with esculin-based VRE media, simplifying colony selection for confirmatory testing.
Enhanced Selectivity: Reduces presumptive false-positive results from other esculin-hydrolyzing organisms that can complicate interpretation of conventional bile-esculin media. (Contains 6mg/L vancomycin.)
📌 This product is labeled for Research Use Only (RUO).
👉 Finished product meets the following standards and references:
CLSI
🧫 Application Areas:
Clinical microbiology for the selective detection and differentiation of vancomycin-resistant Enterococcus (VRE)
Gastrointestinal colonization screening for vanA/vanB-type VRE
Infection prevention and healthcare-associated infection (HAI) surveillance
Multidrug-resistant organism (MDRO) screening and surveillance
Antimicrobial resistance (AMR) surveillance
Healthcare outbreak investigation and containment
Patient screening in high-risk healthcare settings, including ICU and long-term care facilities
Public health and epidemiological surveillance
Clinical laboratory screening and workflow optimization
Equivalent or Comparable to Item Numbers:
CHRP0002
70-C00132
R01830
65751
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