Chameleon™ COLOREX™ C3GR (RUO)
Chameleon™ COLOREX™ C3GR prepared culture media plates by S²Media are manufactured using original CHROMagar™ raw materials. This selective chromogenic culture medium is intended for the qualitative direct detection and differentiation of third-generation cephalosporin-resistant Enterobacterales (C3GR-E) from rectal swabs and stool specimens. Following 18-24 hours of aerobic incubation at 35-37°C, characteristic colony coloration facilitates rapid presumptive identification of resistant organisms, supporting gastrointestinal colonization screening, antimicrobial resistance surveillance, and infection prevention programs. C3GR may also serve as an early indicator of multidrug-resistant organisms but is not intended to diagnose infection or guide antimicrobial therapy. Presumptive isolates should be confirmed by appropriate organism identification, antimicrobial susceptibility testing, and epidemiological characterization.
👉 Key Performance Features:
Rapid Detection: Enables detection of third-generation cephalosporin-resistant Enterobacterales (C3GR-E) following 18-24 hours of aerobic incubation at 35-37°C.
Chromogenic Differentiation: Characteristic colony coloration facilitates presumptive species differentiation of resistant Enterobacterales directly on the primary culture medium.
Direct Specimen Plating: Supports direct culture from rectal swabs and stool specimens without selective pre-enrichment, reducing hands-on time and streamlining laboratory workflow.
Broad β-Lactamase Detection: Selective supplementation supports recovery of third-generation cephalosporin-resistant organisms associated with clinically significant β-lactamase mechanisms.
AmpC Recovery: Formulated to support detection of plasmid-mediated AmpC-producing bacteria without selective inhibition, improving recovery of these resistant organisms.
High Sensitivity: Demonstrated 100% sensitivity (analytical) and 77% (clinical) for the recovery of β-lactam drug resistant Gram-negative bacteria in rectal swabs.
📌 This product is labeled for Research Use Only (RUO).
👉 Finished product meets the following standards and references:
CLSI
🧫 Application Areas:
Clinical microbiology for the selective detection and differentiation of third-generation cephalosporin-resistant Enterobacterales (C3GR-E)
Gastrointestinal colonization screening for multidrug-resistant organisms (MDROs)
β-Lactamase-producing Enterobacterales screening, including plasmid-mediated AmpC producers
Infection prevention and healthcare-associated infection (HAI) surveillance
Antimicrobial resistance (AMR) surveillance
Healthcare outbreak investigation and containment
Public health and epidemiological surveillance
Clinical laboratory screening and workflow optimization
Equivalent or Comparable to Item Numbers:
CHRP0012
70-C00120
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